Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111643 | 0.91 | ALDH1A1 (0.57) | LMNAPKMMAPTGAAALDH1A1 | |
| SCHEMBL23645902 | 0.87 | LMNA (0.54) | LMNAPKMMAPTGAAALDH1A1 | |
| SCHEMBL6192649 | 0.81 | MAPT (0.62) | LMNAMAPTGAACYP2C9CYP2C19 | |
| SCHEMBL25795228 | 0.80 | MAPT (0.46) | LMNAPKMMAPTGAACYP2C9 | |
| SCHEMBL23645937 | 0.80 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL23645905 | 0.79 | TRPV1 (0.57) | MAPTGAACYP2C9CYP2C19KDM4E | |
| SCHEMBL25248113 | 0.76 | ALDH1A1 (0.55) | MAPTGAAALDH1A1 | |
| SCHEMBL30754327 | 0.76 | ALDH1A1 (0.55) | MAPTGAAALDH1A1 | |
| SCHEMBL23666090 | 0.76 | ALDH1A1 (0.55) | MAPTGAAALDH1A1 | |
| SCHEMBL23645910 | 0.75 | ALDH1A1 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897865-B2 | ABHD12 inhibitors and methods of making and using same | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-02-13 | — | — | US | disclosed |
| EP-3793552-B1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | SCRIPPS RESEARCH INST (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20210221790-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2021-07-22 | — | — | US | disclosed |
| US-20210221790-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897865-B2 | ABHD12 inhibitors and methods of making and using same | ABHD12, SAMHD1, ABHD11 | LMNA 4313/4885PKM 4205/4885MAPT 3905/4885 |
| US-20210221790-A1 | ABHD12 INHIBITORS AND METHODS OF MAKING AND USING SAME | ABHD12, SAMHD1, ABHD11 | LMNA 4313/4885PKM 4205/4885MAPT 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.