Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23491483 | 0.79 | HTR7 (0.66) | USP7GAAHTR7LMNAMAPK10 | |
| SCHEMBL19358405 | 0.78 | USP7 (1.00) | USP7GAABTKTRPA1KDM5A | |
| SCHEMBL23645930 | 0.77 | USP7 (0.40) | USP7HTR7TRPA1 | |
| Trifluoroacetic Acid SCHEMBL19358341 | 0.75 | HTR7 (0.54) | USP7HTR7LMNAMAPK10 | |
| SCHEMBL12478207 | 0.75 | HTR7 (0.60) | USP7GAAHTR7LMNAMAPK10 | |
| SCHEMBL23645932 | 0.73 | HTR7 (0.45) | USP7HTR7LMNAMAPK10 | |
| SCHEMBL23645927 | 0.72 | SOS1 (0.47) | USP7GAAHTR7LMNAMAPK10 | |
| SCHEMBL20374171 | 0.71 | ASIC3 (0.49) | USP7XDHKCNH2SCN10ANPY5R | |
| SCHEMBL10819138 | 0.70 | HTR7 (0.57) | HTR7LMNAMAPK10 | |
| SCHEMBL695800 | 0.69 | USP7 (0.53) | USP7BTKXDHKCNH2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221813-A1 | 4,6 DIHYDROPYRROLO [3,4-C] PYRAZOLE-5 (1H)-CARBONITRILE DERIVATES FOR TREATING CANCER | MISSION THERAPEUTICS LIMITED (AE) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221813-A1 | 4,6 DIHYDROPYRROLO [3,4-C] PYRAZOLE-5 (1H)-CARBONITRILE DERIVATES FOR TREATING CANCER | USP7, USP1, USP3 | USP7 1/4885GAA 1833/4885HTR7 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.