Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248049 | 0.87 | NPSR1 (0.48) | TGM2NPSR1RXFP1RORC | |
| SCHEMBL16634476 | 0.79 | ALDH1A1 (0.47) | TGM2NPSR1RXFP1RORC | |
| SCHEMBL14750323 | 0.78 | BTK (0.46) | TGM2BTKEGFR | |
| SCHEMBL15356556 | 0.78 | ITK (0.43) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL16634519 | 0.78 | TGM2 (0.44) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL15359415 | 0.77 | TGM2 (0.41) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL28900078 | 0.75 | TTR (0.45) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL16634504 | 0.75 | ALDH1A1 (0.44) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL28900184 | 0.75 | TGM2 (0.44) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL30935269 | 0.74 | BTK (0.47) | TGM2BTKJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7988685-B2 | Hydrogel compositions, devices, and microscale components | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20040248326-A1 | Hydrogel compositions, devices, and microscale components | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-12-09 | — | — | US | disclosed |
| WO-2003051286-A2 | HYDROGEL COMPOSITIONS, DEVICES, AND MICROSCALE COMPONENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-06-26 | — | — | WO | disclosed |