Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399643 | 0.84 | MAPT (0.61) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL25386626 | 0.82 | NFE2L2 (0.55) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30334863 | 0.82 | NFE2L2 (0.55) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL28317228 | 0.82 | ALDH1A1 (0.53) | HSPB1MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL515302 | 0.82 | LMNA (0.61) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL28218708 | 0.82 | LMNA (0.61) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30059246 | 0.82 | LMNA (0.61) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10829168 | 0.81 | NFE2L2 (0.61) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30612688 | 0.81 | NFE2L2 (0.59) | NFE2L2MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL28090002 | 0.81 | NFE2L2 (0.59) | NFE2L2MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143706-A1 | SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2021-07-22 | — | — | WO | disclosed |