SCHEMBL236486

SCHEMBL236486

O=C(Oc1ccccc1-c1ccc(-c2ccc3ccccc3c2)cc1)Oc1ccccc1-c1ccc(-c2ccc3ccccc3c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
GSTP1 P09211 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
ALOX5 P09917 1/20 0.43
FFAR4 Q5NUL3 2/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2286078 0.93 SLC6A3 (0.54) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL236487 0.89 ESR1 (0.47) ESR1ESR2SLC6A2SLC6A4SLC6A3
Bicarbonate SCHEMBL28016111 0.88 ESR1 (0.46) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL30462994 0.88 FFAR4 (0.50) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL236822 0.83 FABP3 (0.53) FFAR4KDM4ELMNATSHRFABP7
SCHEMBL2286083 0.82 SLC6A2 (0.53) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL236488 0.81 ESR1 (0.57) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL237166 0.81 ESR1 (0.57) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL29672387 0.81 ESR1 (0.57) ESR1ESR2SLC6A2SLC6A4SLC6A3
SCHEMBL27659147 0.81 SLC6A2 (0.51) ESR1ESR2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20210371609-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO LLC 2021-12-02 US disclosed
EP-3707198-B1 PLASTIC FILMS WITH REDUCED UV ACTIVITY COVESTRO DEUTSCHLAND AG (DE) 2021-10-27 EP disclosed
EP-3707198-A1 PLASTIC FILMS WITH REDUCED UV ACTIVITY Covestro Deutschland AG (DE) 2020-09-16 EP disclosed
EP-3645297-A1 IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2020-05-06 EP disclosed
EP-3038747-B1 TRANSESTERIFICATION OF AROMATIC ALCOHOLS USING A HETEROGENEOUS CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-08 EP disclosed
EP-3630875-A1 FILMS HAVING A SCRATCH-RESISTANT COATING AS A COVER LAYER AND LAYERED COMPOSITES COMPRISING SUCH FILMS Covestro Deutschland AG (DE) 2020-04-08 EP disclosed
EP-3383835-B1 A METHOD FOR RECOVERING AN AROMATIC ALCOHOL FROM A MELT POLYMERIZATION, AND A SYSTEM FOR RECOVERING THE SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-07-24 EP disclosed
WO-2019048986-A1 METHOD FOR PRODUCING A POLYCARBONATE ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-14 WO disclosed
US-10131178-B2 Layered structure and films for ID documents having improved properties for laser engraving COVESTRO DEUTSCHLAND AG (DE) 2018-11-20 US disclosed
US-20110206568-A1 PROCESS FOR THE PREPARATION OF DIARYL CARBONATES OR ARYLALKYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2011-08-25 US disclosed
US-8003817-B2 Process for the preparation of diaryl carbonates or arylalkyl carbonates from dialkyl carbonates BAYER MATERIALSCIENCE AG (DE) 2011-08-23 US disclosed
US-7814626-B2 Process for the preparation of polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2010-10-19 US disclosed
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES BAYER MATERIALSCIENCE AG (DE) 2009-03-19 US disclosed
US-20080319156-A1 Process For The Preparation Of Polycarbonate By The Melt Transesterification Process BAYER MATERIALSCIENCE AG (DE) 2008-12-25 US disclosed
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates BAYER MATERIALSCIENCE AG (DE) 2008-11-27 US disclosed
US-7250483-B2 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2007-07-31 US disclosed
US-7091302-B2 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG (DE) 2006-08-15 US disclosed
US-20060004178-A1 Inhibition of catalytically active impurities in polycarbonate by the melt transesterification process COVESTRO DEUTSCHLAND AG (DE) 2006-01-05 US disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293960-A1 Process For The Preparation Of Diaryl Carbonates Or Arylalkyl Carbonates From Dialkyl Carbonates HDHD5, ALKBH3, AHR ESR1 1516/4885ESR2 2633/4885SLC6A2 2827/4885
US-20090076293-A1 PROCESSES FOR PREPARING DIARYL AND/OR ALKYLARYL CARBONATES FROM DIALKYL CARBONATES DHCR7, ADH1C, AKR1C4 ESR1 1450/4885ESR2 1883/4885SLC6A2 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.