Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26707214 | 0.84 | MGLL (0.42) | AKT1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL21780805 | 0.84 | MGLL (0.42) | AKT1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL20041101 | 0.83 | AKT1 (0.45) | AKT1ALDH1A1POLBHSD17B10 | |
| SCHEMBL24581817 | 0.83 | AKT1 (0.44) | AKT1KMT2A | |
| SCHEMBL24240484 | 0.82 | MGLL (0.40) | AKT1LMNAKMT2AALDH1A1POLB | |
| SCHEMBL16485195 | 0.81 | AKT1 (0.49) | AKT1ALDH1A1 | |
| SCHEMBL16484778 | 0.81 | AKT1 (0.41) | AKT1LMNAALDH1A1POLBHSD17B10 | |
| SCHEMBL29331543 | 0.81 | LMNA (0.52) | RAB9ALMNAKMT2AALDH1A1POLB | |
| SCHEMBL25834988 | 0.81 | POLB (0.44) | RAB9ALMNAKMT2AALDH1A1POLB | |
| SCHEMBL24798058 | 0.81 | FNTA (0.38) | AKT1KMT2AALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3595668-B1 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS INC (US) | 2021-07-21 | — | — | EP | disclosed |