Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645378 | 0.72 | RIPK1 (0.34) | POLBRIPK1 | |
| SCHEMBL23645393 | 0.71 | POLB (0.37) | POLBRIPK1 | |
| SCHEMBL21331023 | 0.69 | PDK1 (0.39) | KMOPOLBRIPK1 | |
| SCHEMBL23652632 | 0.67 | FFAR4 (0.32) | KMORIPK1 | |
| SCHEMBL1423129 | 0.66 | MGLL (0.40) | KMOPOLB | |
| SCHEMBL31069289 | 0.66 | RIPK1 (0.42) | RIPK1 | |
| SCHEMBL23645421 | 0.66 | GRM2 (0.38) | POLBRIPK1 | |
| SCHEMBL23645567 | 0.66 | RIPK1 (0.42) | RIPK1 | |
| SCHEMBL23652782 | 0.66 | — | — | |
| SCHEMBL23645451 | 0.65 | KMO (0.32) | KMORIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851436-A1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2021-07-21 | — | — | EP | disclosed |