Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365327 | 0.87 | KDM4E (0.40) | TEAD1TEAD3LTA4HPARP15PARP10 | |
| SCHEMBL2365536 | 0.85 | LIPE (0.36) | TEAD1TEAD3LTA4HPARP15PARP10 | |
| SCHEMBL2363075 | 0.85 | S1PR5 (0.40) | — | |
| SCHEMBL2365423 | 0.85 | LTA4H (0.35) | TEAD1TEAD3LTA4HPARP15PARP10 | |
| SCHEMBL2365577 | 0.83 | HRH2 (0.37) | TEAD1TEAD3LTA4HMRGPRX4MEN1 | |
| SCHEMBL2365496 | 0.83 | TEAD1 (0.36) | TEAD1TEAD3LTA4HMRGPRX4MEN1 | |
| SCHEMBL2365504 | 0.83 | ACKR3 (0.42) | TEAD1TEAD3LTA4HPARP15PARP10 | |
| SCHEMBL2365528 | 0.81 | FFAR1 (0.36) | TEAD1TEAD3ACACBHCRTR1HCRTR2 | |
| SCHEMBL2365345 | 0.80 | ALDH1A1 (0.37) | MEN1KMT2ADRD2 | |
| SCHEMBL2365397 | 0.80 | TEAD1 (0.32) | TEAD1TEAD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |