Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365345 | 0.91 | ALDH1A1 (0.37) | KDM4EALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL2365374 | 0.87 | TEAD1 (0.35) | PARP15PARP10LTA4HTEAD1TEAD3 | |
| SCHEMBL2363075 | 0.86 | S1PR5 (0.40) | L3MBTL1TP53 | |
| SCHEMBL2365423 | 0.86 | LTA4H (0.35) | CHRM4ALDH1A1PARP15PARP10LTA4H | |
| SCHEMBL2365536 | 0.86 | LIPE (0.36) | PARP15PARP10LTA4HEPHX2TEAD1 | |
| SCHEMBL2365504 | 0.85 | ACKR3 (0.42) | PARP15PARP10LTA4HTEAD1TEAD3 | |
| SCHEMBL2363548 | 0.83 | KDM4E (0.43) | KDM4ECHRM4ALDH1A1LMNAHTT | |
| SCHEMBL2365528 | 0.81 | FFAR1 (0.36) | ALDH1A1EPHX2TEAD1TEAD3FFAR1 | |
| SCHEMBL2365397 | 0.81 | TEAD1 (0.32) | TEAD1TEAD3 | |
| SCHEMBL2365446 | 0.80 | POLB (0.38) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |