SCHEMBL23655191

SCHEMBL23655191

Cc1ccccc1-c1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.49
KIF11 P52732 2/20 0.47
MMP3 P08254 1/20 0.47
ALDH1A1 P00352 3/20 0.46
CYP2A6 P11509 1/20 0.46
CYP11B2 P19099 4/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
CYP11B1 P15538 1/20 0.46
TSHR P16473 2/20 0.44
PDK2 Q15119 1/20 0.42
ATM Q13315 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4877065 0.98 AR (0.50) ARKIF11MMP3ALDH1A1CYP2A6
SCHEMBL20407070 0.84 PGR (0.49) ARALDH1A1PDK2
SCHEMBL31463164 0.83 TSHR (0.57) KIF11MMP3ALDH1A1CYP2A6CYP11B2
SCHEMBL4541662 0.82 CA12 (0.59) ARALDH1A1CA12CA1CA2
SCHEMBL29551646 0.82 CA12 (0.59) ARALDH1A1CA12CA1CA2
SCHEMBL10304744 0.82 ALDH1A1 (0.45) ARKIF11MMP3ALDH1A1CYP2A6
SCHEMBL23625616 0.81 AR (0.44) ARKIF11MMP3ALDH1A1CYP2A6
SCHEMBL20405268 0.80 ESR2 (0.63) ARALDH1A1CA12CA1CA2
SCHEMBL27806613 0.80 KIF11 (0.47) KIF11MMP3ALDH1A1CYP2A6CYP11B2
SCHEMBL18406713 0.80 AR (0.49) ARALDH1A1CYP11B2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351536-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2021-07-21 EP disclosed