SCHEMBL23625616

SCHEMBL23625616

Cc1cccc(-c2ccc(C#N)cc2)c1C#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.44
CYP11B2 P19099 3/20 0.44
CYP2A6 P11509 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP11B1 P15538 1/20 0.40
KIF11 P52732 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
MMP3 P08254 1/20 0.39
SCN8A Q9UQD0 1/20 0.39
EGLN2 Q96KS0 1/20 0.39
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12681320 0.86 LOXL2 (0.46) ARCYP11B2CYP2A6ALDH1A1KIF11
SCHEMBL23625539 0.85 ALDH1A1 (0.59) ARCYP11B2CYP2A6ALDH1A1CYP11B1
SCHEMBL3376658 0.85 ALDH1A1 (0.49) ALDH1A1CYP1A2CYP2C19TSHRHSD17B10
SCHEMBL8845798 0.84 SMN1; SMN2 (0.45) ALDH1A1CYP1A2CYP2C19TSHRHSD17B10
SCHEMBL10304744 0.83 ALDH1A1 (0.45) ARCYP11B2CYP2A6ALDH1A1CYP11B1
SCHEMBL4877065 0.82 AR (0.50) ARCYP11B2CYP2A6ALDH1A1CYP11B1
SCHEMBL21189094 0.82 ADRA2C (0.49) ARCYP1A2CYP2C19KDM4E
SCHEMBL23655191 0.81 AR (0.49) ARCYP11B2CYP2A6ALDH1A1CYP11B1
SCHEMBL24451136 0.80 ALDH1A1 (0.50) CYP11B2CYP2A6ALDH1A1KIF11LOXL2
SCHEMBL13365649 0.79 CYP11B2 (0.46) CYP11B2CYP2A6ALDH1A1CYP11B1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed