Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.64 |
| ▸ | HTR1A | P08908 | 12/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657287 | 0.94 | HTR1A (0.58) | MPOHTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23657438 | 0.92 | MPO (0.62) | MPOHTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23657417 | 0.91 | HTR1A (0.55) | MPOHTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23657424 | 0.91 | HTR1A (0.55) | MPOHTR1ASLC6A4HTR7KCNH2 | |
| SCHEMBL23657396 | 0.90 | HTR1A (0.51) | MPOHTR1A | |
| SCHEMBL23657420 | 0.90 | HTR1A (0.64) | HTR1A | |
| SCHEMBL23657405 | 0.90 | HTR1A (0.51) | MPOHTR1AKCNH2 | |
| SCHEMBL23657419 | 0.90 | HTR1A (0.59) | MPOHTR1ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL23657434 | 0.89 | HTR1A (0.53) | MPOHTR1ASLC6A4 | |
| SCHEMBL23657181 | 0.88 | HTR1A (0.55) | MPOHTR1ASLC6A4HTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |