Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | HTR1D | P28221 | 7/20 | 0.55 |
| ▸ | HTR1B | P28222 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SPR | P35270 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657266 | 0.85 | KCNA5 (0.64) | HTR1AHTR1DHTR1BKDM4EMAPT | |
| SCHEMBL23657358 | 0.80 | KCNA5 (0.60) | HTR1AHTR1DHTR1BKDM4EMAPT | |
| SCHEMBL29824627 | 0.80 | KCNA5 (0.74) | HTR1AHTR1DHTR1BKDM4EMEN1 | |
| SCHEMBL23648916 | 0.80 | KCNA5 (0.74) | HTR1AHTR1DHTR1BKDM4EMEN1 | |
| SCHEMBL23657162 | 0.78 | KCNA5 (0.58) | HTR1AHTR1DHTR1BKDM4ECYP2D6 | |
| SCHEMBL22953701 | 0.76 | MPO (0.72) | HTR1AHTR1DHTR1BKDM4ECYP2D6 | |
| SCHEMBL25077001 | 0.76 | HTR2C (0.72) | HTR1AHTR1DHTR1BKDM4ECYP2D6 | |
| SCHEMBL15136550 | 0.75 | TRPV1 (0.80) | KDM4ECYP2D6TRPV1MAPTNPSR1 | |
| SCHEMBL6987521 | 0.75 | SLC6A4 (0.71) | HTR1AHTR1DHTR1BKDM4ECYP2D6 | |
| SCHEMBL453066 | 0.75 | TRPV1 (0.67) | HTR1AHTR1DHTR1BKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |