Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177163 | 0.82 | THRA (0.47) | THRATHRBMAOBTDP1IGF1R | |
| SCHEMBL9670640 | 0.79 | THRA (0.50) | THRATHRBMAOBTDP1ESR1 | |
| SCHEMBL9673266 | 0.79 | THRA (0.50) | THRATHRBMAOBTDP1ESR1 | |
| SCHEMBL9673289 | 0.79 | THRA (0.50) | THRATHRBMAOBTDP1ESR1 | |
| SCHEMBL9670792 | 0.79 | THRA (0.50) | THRATHRBMAOBTDP1ESR1 | |
| SCHEMBL7621783 | 0.78 | THRA (0.44) | THRATHRBESR1ADRA2AADORA3 | |
| SCHEMBL2022281 | 0.77 | CA2 (0.48) | THRATHRBKCNH2ESR1ADRA2A | |
| SCHEMBL1008937 | 0.76 | IGF1R (0.53) | MAOBIGF1RALOX15KCNH2 | |
| SCHEMBL9552268 | 0.75 | RARB (0.47) | THRATHRBMAOBTDP1KDM4E | |
| SCHEMBL9303786 | 0.75 | TRPA1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |