Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657356 | 0.89 | MEN1 (0.59) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL23657370 | 0.84 | MEN1 (0.56) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL23657387 | 0.80 | PDGFRB (0.49) | ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL23648910 | 0.80 | MAPT (0.53) | ACHEALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL23657212 | 0.78 | HRH3 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5639533 | 0.76 | ACHE (0.88) | ACHEALDH1A1SMN1; SMN2ATP4AATP4B | |
| SCHEMBL23657403 | 0.74 | HRH3 (0.54) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9521781 | 0.74 | POLB (0.72) | ACHEALDH1A1NPC1RAB9APKM | |
| SCHEMBL23657359 | 0.73 | SLC6A4 (0.58) | ACHEMAPT | |
| SCHEMBL9519818 | 0.73 | POLB (0.75) | ACHEALDH1A1CYP2D6CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |