Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ATP4A | P20648 | 1/20 | 0.48 |
| ▸ | ATP4B | P51164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657370 | 0.94 | MEN1 (0.56) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23657354 | 0.89 | ACHE (0.53) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23657363 | 0.79 | MTNR1A (0.45) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23649505 | 0.78 | KCNA5 (0.60) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23649382 | 0.75 | KCNA5 (0.57) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23657266 | 0.74 | KCNA5 (0.64) | ALDH1A1MAPT | |
| SCHEMBL13406174 | 0.74 | ALDH1A1 (0.84) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL379648 | 0.73 | POLB (0.79) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL594026 | 0.73 | ALDH1A1 (0.62) | MEN1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8948422 | 0.72 | NPC1 (0.71) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |