Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200588 | 0.85 | ALDH1A1 (0.62) | KDM4ERAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL30216783 | 0.83 | KDM4E (0.82) | KDM4ERAB9ATP53TSHRNFKB1 | |
| SCHEMBL21709858 | 0.83 | KDM4E (0.82) | KDM4ERAB9ATP53TSHRNFKB1 | |
| SCHEMBL16623348 | 0.79 | TRPV1 (0.76) | KDM4ERAB9ASMN1; SMN2NPC1TRPV1 | |
| SCHEMBL14640504 | 0.79 | TRPV1 (0.76) | KDM4ERAB9ASMN1; SMN2NPC1TRPV1 | |
| SCHEMBL26373265 | 0.79 | KDM4E (0.75) | KDM4ERAB9ATP53TSHRNFKB1 | |
| SCHEMBL28665240 | 0.79 | RAB9A (0.85) | KDM4ERAB9ATP53TSHRNFKB1 | |
| SCHEMBL28397450 | 0.77 | KDM4E (0.73) | KDM4ERAB9ATP53TSHRNFKB1 | |
| SCHEMBL16363401 | 0.77 | ABL1 (0.62) | KDM4ESMN1; SMN2TRPV1MAPT | |
| SCHEMBL15291351 | 0.77 | KDM4E (0.64) | KDM4ERAB9ATP53TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | KDM4E 1784/4885RAB9A 4056/4885TP53 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.