Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.88 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.88 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CASP1 | P29466 | 1/20 | 0.71 |
| ▸ | CASP7 | P55210 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525575 | 0.83 | HPGD (1.00) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL12562441 | 0.79 | MEN1 (0.74) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL17624914 | 0.75 | PIM1 (0.71) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL17624916 | 0.73 | MAPT (0.58) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL4899880 | 0.71 | KDM4E (0.62) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL6217262 | 0.71 | MAPT (0.86) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL17624913 | 0.71 | MEN1 (0.63) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL7496360 | 0.70 | MAPT (0.84) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL4194506 | 0.70 | LIMK1 (0.82) | HPGDMAPTKDM4EALDH1A1MEN1 | |
| Lithium Ion SCHEMBL7496352 | 0.69 | MAPT (0.82) | HPGDMAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | HPGD 512/4885MAPT 4875/4885KDM4E 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.