SCHEMBL2365907

SCHEMBL2365907

CNC(=O)CC=CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
GABRR1 P24046 2/20 0.42
GABRR2 P28476 2/20 0.42
BLM P54132 2/20 0.42
LMNA P02545 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
APEX1 P27695 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
HCAR2 Q8TDS4 3/20 0.36
MCL1 Q07820 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6964609 0.75
SCHEMBL2619500 0.75
SCHEMBL6340506 0.73
SCHEMBL7803946 0.73
SCHEMBL12267828 0.73
SCHEMBL10584847 0.73
SCHEMBL12433479 0.73 MCL1 (0.41) LMNATDP1MCL1ALDH1A1CYP2D6
SCHEMBL17391220 0.73 TSHR (0.39) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL27999002 0.73 ALDH1A1 (0.41) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL38650658 0.73 L3MBTL1 (0.39) TSHRGABRR1GABRR2BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9884317-B2 Inorganic/polymeric hybrid catalytic materials with high activity in various solvents NIPPON KODOSHI CORPORATION (JP) 2018-02-06 US disclosed
US-9527067-B2 Inorganic/polymeric hybrid catalytic materials containing metal nano-particles therein NIPPON KODOSHI CORPORATION (JP) 2016-12-27 US disclosed
US-20150005154-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS WITH HIGH ACTIVITY IN VARIOUS SOLVENTS NIPPON KODOSHI CORPORATION (JP) 2015-01-01 US disclosed
EP-2814607-A1 INORGANIC / POLYMERIC HYBRID CATALYTIC MATERIALS WITH HIGH ACTIVITY IN VARIOUS SOLVENTS Nippon Kodoshi Corporation (JP) 2014-12-24 EP disclosed
US-20140128251-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS CONTAINING METAL NANO-PARTICLES THEREIN NIPPON KODOSHI CORPORATION (JP) 2014-05-08 US disclosed
EP-2688668-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS CONTAINING METAL NANO-PARTICLES THEREIN Nippon Kodoshi Corporation (JP) 2014-01-29 EP disclosed
EP-2364987-B1 Axially asymmetric phosphorus compound and production method thereof UNIV TOKYO NAT UNIV CORP (JP) 2013-11-20 EP disclosed
WO-2013121593-A1 INORGANIC / POLYMERIC HYBRID CATALYTIC MATERIALS WITH HIGH ACTIVITY IN VARIOUS SOLVENTS NIPPON KODOSHI CORPORATION (JP) 2013-08-22 WO disclosed
WO-2012176341-A1 INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS CONTAINING METAL NANO-PARTICLES THEREIN NIPPON KODOSHI CORPORATION (JP) 2012-12-27 WO disclosed
US-8222433-B2 Axially asymmetric phosphorus compound and production method thereof NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY (JP) 2012-07-17 US disclosed
EP-2364987-A1 Axially asymmetric phosphorus compound and production method thereof National University Corporation Tokyo University of Agriculture and Technology (JP) 2011-09-14 EP disclosed
US-20110218345-A1 AXIALLY ASYMMETRIC PHOSPHORUS COMPOUND AND PRODUCTION METHOD THEREOF TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-09-08 US disclosed
EP-0984972-B1 CHIRAL PHOSPHORUS-BASED LIGANDS CHIROTECH TECHNOLOGY LTD (GB) 2002-07-31 EP disclosed
US-6156935-A Chiral phosphorus-based ligands CHIROTECH TECHNOLOGY, LTD. (GB) 2000-12-05 US disclosed
EP-0984972-A1 CHIRAL PHOSPHORUS-BASED LIGANDS Chirotech Technology Limited (GB) 2000-03-15 EP disclosed
WO-1998054193-A1 CHIRAL PHOSPHORUS-BASED LIGANDS CHIROTECH TECHNOLOGY LIMITED (GB) 1998-12-03 WO disclosed
US-4879398-A Process for producing 2,6-disubstituted tyrosine MONSANTO COMPANY (US) 1989-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218345-A1 AXIALLY ASYMMETRIC PHOSPHORUS COMPOUND AND PRODUCTION METHOD THEREOF SOST, PHOSPHO1, PPIP5K2 TSHR 889/4885GABRR1 726/4885GABRR2 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.