Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4343330 | 0.79 | — | — | |
| SCHEMBL2423251 | 0.77 | — | — | |
| SCHEMBL22221540 | 0.77 | — | — | |
| SCHEMBL783333 | 0.77 | — | — | |
| SCHEMBL18743786 | 0.76 | — | — | |
| SCHEMBL7569975 | 0.76 | ALDH1A1 (0.39) | DPP4 | |
| SCHEMBL7348552 | 0.74 | ALDH1A1 (0.40) | DPP4 | |
| SCHEMBL1378572 | 0.74 | — | — | |
| SCHEMBL5017599 | 0.72 | KISS1R (0.35) | MAOAMAOBDPP4 | |
| SCHEMBL20635099 | 0.72 | MAOA (0.35) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021144746-A1 | USE OF ICRF-193 DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF FOR THE PREVENTION OF CHRONIC CUMULATIVE CARDIOTOXICITY CAUSED BY THERAPY WITH ANTHRACYCLINE ANTICANCER DRUGS | UNIVERZITA KARLOVA V PRAZE (CZ) | 2021-07-22 | — | — | WO | disclosed |