Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348552 | 0.81 | ALDH1A1 (0.40) | DPP4ALDH1A1 | |
| SCHEMBL2423251 | 0.76 | — | — | |
| SCHEMBL783333 | 0.76 | — | — | |
| SCHEMBL18743786 | 0.74 | — | — | |
| SCHEMBL23660732 | 0.72 | MAOA (0.36) | DPP4MAOAMAOB | |
| SCHEMBL27855767 | 0.72 | ECE1 (0.37) | KISS1RDPP4ALDH1A1 | |
| SCHEMBL1378572 | 0.72 | — | — | |
| SCHEMBL7345987 | 0.72 | ALDH1A1 (0.41) | DPP4ALDH1A1 | |
| SCHEMBL27327324 | 0.71 | — | — | |
| SCHEMBL15389112 | 0.71 | ALDH1A1 (0.42) | DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648905-B1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | disclosed |