Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003574 | 0.93 | AKR1C3 (0.36) | ESR1ESR2AKR1C3AKR1C2AKR1B10 | |
| SCHEMBL19820209 | 0.84 | AKR1C3 (0.42) | AKR1C3AKR1C2 | |
| SCHEMBL23666664 | 0.84 | AKR1C3 (0.34) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL18948448 | 0.82 | NR1I2 (0.46) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL20414528 | 0.80 | AR (0.37) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL21125230 | 0.78 | AKR1C3 (0.43) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL21125000 | 0.78 | AKR1C3 (0.38) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL28411135 | 0.77 | AKR1C3 (0.42) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL20178592 | 0.76 | CFTR (0.43) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL19003629 | 0.76 | CTSS (0.39) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221781-A1 | FATTY ACID ANALOGUES AND METHODS OF USE | LIN BIOSCIENCE INC. (TW) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221781-A1 | FATTY ACID ANALOGUES AND METHODS OF USE | ELOVL1, FADS1, ALOX5 | ESR1 2726/4885ESR2 1639/4885AKR1C3 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.