Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820018 | 0.95 | FFAR4 (0.46) | CDYLKDM4ENQO2MTNR1ANR1D1 | |
| SCHEMBL7286194 | 0.88 | CDYL (0.56) | CDYLKDM4ENQO2MTNR1ANR1D1 | |
| SCHEMBL28672892 | 0.85 | CYP4F2 (0.49) | KDM4EMTNR1AL3MBTL1ALDH1A1 | |
| SCHEMBL28510004 | 0.82 | TAAR1 (0.38) | KDM4EALDH1A1S1PR1 | |
| SCHEMBL28676646 | 0.81 | HTT (0.42) | MTNR1ACTSSCTSKFFAR4ALDH1A1 | |
| SCHEMBL13225857 | 0.81 | MEN1 (0.39) | MTNR1A | |
| SCHEMBL1180264 | 0.80 | TDP1 (0.56) | CDYLKDM4EMTNR1AFFAR4TDP1 | |
| SCHEMBL8480197 | 0.80 | CDYL (0.49) | CDYLKDM4ENQO2MTNR1AFFAR4 | |
| SCHEMBL4564283 | 0.79 | MTNR1A (0.54) | CDYLKDM4EMTNR1AFFAR4TDP1 | |
| SCHEMBL4510057 | 0.79 | TDP1 (0.54) | CDYLKDM4EMTNR1AFFAR4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364704-A1 | Combination of beta-adrenoceptor agonist and corticosteroid | AstraZeneca AB (SE) | 2011-09-14 | — | — | EP | disclosed |