Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.54 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180264 | 0.86 | TDP1 (0.56) | MTNR1ACDYLTDP1MEN1KMT2A | |
| SCHEMBL4510057 | 0.85 | TDP1 (0.54) | MTNR1ACDYLTDP1MEN1KMT2A | |
| SCHEMBL961507 | 0.84 | MTNR1A (0.63) | MTNR1ACDYLTDP1MEN1KMT2A | |
| SCHEMBL586305 | 0.83 | CYP1A2 (0.52) | MTNR1ACDYLTDP1AKR1B1 | |
| SCHEMBL1284856 | 0.82 | MTNR1A (0.62) | MTNR1ATDP1MEN1KMT2APARP10 | |
| Naphthalene SCHEMBL1848110 | 0.80 | FFAR4 (0.50) | MTNR1ACDYLTDP1KMT2AFFAR4 | |
| SCHEMBL6421722 | 0.80 | MTNR1A (0.58) | MTNR1ACDYLTDP1MEN1KMT2A | |
| SCHEMBL14966254 | 0.80 | FDPS (0.39) | MTNR1ATDP1MEN1KMT2AKDM4E | |
| SCHEMBL2366865 | 0.79 | CDYL (0.48) | MTNR1ACDYLTDP1FFAR4KDM4E | |
| SCHEMBL4521520 | 0.79 | MTNR1A (0.45) | MTNR1ACDYLTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118084-A1 | SALTS 668 | AstraZeneca AB (SE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008096112-A1 | SALTS 668 | ASTRAZENECA AB (SE) | 2008-08-14 | — | — | WO | disclosed |