Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180264 | 0.98 | TDP1 (0.56) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| Naphthalene SCHEMBL1848110 | 0.92 | FFAR4 (0.50) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| SCHEMBL1820018 | 0.86 | FFAR4 (0.46) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| SCHEMBL4564283 | 0.85 | MTNR1A (0.54) | TDP1FFAR4FFAR1AKR1B1KDM4E | |
| SCHEMBL48684 | 0.84 | TDP1 (0.57) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| SCHEMBL7791197 | 0.84 | FFAR4 (0.48) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| SCHEMBL586305 | 0.83 | CYP1A2 (0.52) | TDP1AKR1B1CYP1A2CDYLMTNR1A | |
| SCHEMBL1218835 | 0.82 | TDP1 (0.67) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| SCHEMBL30307853 | 0.82 | TDP1 (0.67) | TDP1FFAR4FFAR1AKR1B1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11319694 | 0.80 | TDP1 (0.65) | TDP1FFAR4FFAR1AKR1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ADRB2, ADRB1, ADRA2C | TDP1 4235/4885FFAR4 313/4885FFAR1 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.