Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727214 | 0.82 | GSK3B (0.43) | GSK3BTSHRALOX15MAPTALDH1A1 | |
| SCHEMBL2367271 | 0.65 | MAPT (0.47) | TSHRALOX15MAPTALDH1A1TP53 | |
| SCHEMBL27786410 | 0.64 | CYP2A13 (0.67) | TSHRMAPK1ALOX15MAPTALDH1A1 | |
| SCHEMBL14373088 | 0.62 | HTR2A (0.48) | MAPTALDH1A1DRD2TP53KMT2A | |
| SCHEMBL31752630 | 0.60 | CETP (0.37) | OPRM1 | |
| SCHEMBL31751581 | 0.60 | CETP (0.37) | OPRM1 | |
| SCHEMBL10727127 | 0.59 | ALDH1A1 (0.47) | TSHRALOX15MAPTALDH1A1DRD2 | |
| SCHEMBL14280680 | 0.59 | OPRM1 (1.00) | OPRM1OPRK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL31753319 | 0.58 | LTA4H (0.34) | GSK3BALDH1A1GPBAR1TP53KMT2A | |
| SCHEMBL31752809 | 0.58 | LTA4H (0.34) | GSK3BALDH1A1GPBAR1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | claimed |