Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ITK | Q08881 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18354072 | 0.90 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2EPHX2GAATDP1 | |
| SCHEMBL2025761 | 0.84 | TDP1 (0.50) | ZDHHC20ZDHHC2GAATDP1TGM2 | |
| SCHEMBL29004029 | 0.84 | ZDHHC20 (0.38) | ZDHHC20ZDHHC2EPHX2GAATDP1 | |
| SCHEMBL20841213 | 0.83 | TDP1 (0.49) | ZDHHC20ZDHHC2GAATDP1TGM2 | |
| SCHEMBL20243379 | 0.82 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2EPHX2GAATDP1 | |
| SCHEMBL12328963 | 0.81 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2GAATDP1ALDH1A1 | |
| SCHEMBL19141793 | 0.79 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2GAATDP1ALDH1A1 | |
| SCHEMBL5530407 | 0.79 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2GAATDP1ALDH1A1 | |
| SCHEMBL9889645 | 0.79 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2GAATDP1ALDH1A1 | |
| SCHEMBL24715024 | 0.79 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2GAATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11071693-B2 | Direct dental filling composition | DENTSPLY SIRONA INC. (US) | 2021-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11071693-B2 | Direct dental filling composition | CAD, DOCK5, ITGA5 | ZDHHC20 2812/4885ZDHHC2 3526/4885EPHX2 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.