SCHEMBL18354072

SCHEMBL18354072

C=CC(=O)NCCCC(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
EPHX2 P34913 1/20 0.44
GAA P10253 2/20 0.43
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TGM2 P21980 3/20 0.38
FPR3 P25089 1/20 0.37
FPR2 P25090 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
LMNA P02545 1/20 0.35
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23675898 0.90 ZDHHC20 (0.44) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL18362467 0.84 ZDHHC20 (0.40) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL20243379 0.83 ZDHHC20 (0.41) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL26478859 0.82 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL23413291 0.82 CA14 (0.41) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL29004029 0.81 ZDHHC20 (0.38) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL31672311 0.81 TDP1 (0.62) ZDHHC20ZDHHC2GAATDP1ALDH1A1
SCHEMBL15575825 0.81 TDP1 (0.57) ZDHHC20ZDHHC2GAATDP1ALDH1A1
SCHEMBL9138923 0.80 TSHR (0.46) ZDHHC20ZDHHC2EPHX2GAATDP1
SCHEMBL7713907 0.80 TDP1 (0.65) ZDHHC20ZDHHC2GAATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839657-B2 Ionizable lipids and compositions for nucleic acid delivery WESTGENE BIOPHARMA CO., LTD (CN) 2023-12-12 US disclosed
CN-108064253-B Polymer matrices formed from carboxy-functional acrylamides 生命技术公司 2020-09-15 CN disclosed
EP-3702383-A1 POLYMER SUBSTRATES FORMED FROM CARBOXY FUNCTIONAL ACRYLAMIDE Life Technologies Corporation (US) 2020-09-02 EP disclosed
US-10676790-B2 Conjugation of carboxyl functional hydrophilic beads Life Technologies Corporation (US) 2020-06-09 US disclosed
US-10189956-B2 Polymer substrates formed from carboxy functional acrylamide LIFE TECHNOLOGIES AS (NO) 2019-01-29 US disclosed
US-9868826-B2 Polymer substrates formed from carboxy functional acrylamide Life Technologies Corporation (US) 2018-01-16 US disclosed
US-9868826-B2 Polymer substrates formed from carboxy functional acrylamide Life Technologies Corporation (US) 2018-01-16 US disclosed
US-20170002410-A1 Conjugation Of Carboxyl Functional Hydrophilic Beads Life Technologies Corporation 2017-01-05 US disclosed
US-20170002410-A1 Conjugation Of Carboxyl Functional Hydrophilic Beads Life Technologies Corporation 2017-01-05 US disclosed
WO-2017004556-A1 POLYMER SUBSTRATES FORMED FROM CARBOXY FUNCTIONAL ACRYLAMIDE Life Technologies Corporation (US) 2017-01-05 WO disclosed
US-20170002152-A1 Polymer Substrates Formed From Carboxy Functional Acrylamide Life Technologies Corporation 2017-01-05 US disclosed
US-20170002152-A1 Polymer Substrates Formed From Carboxy Functional Acrylamide Life Technologies Corporation 2017-01-05 US disclosed
WO-2017004559-A1 CONJUGATION OF CARBOXYL FUNCTIONAL HYDROPHILIC BEADS Life Technologies Corporation (US) 2017-01-05 WO disclosed
US-9181364-B2 Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants RELYPSA, INC. (US) 2015-11-10 US disclosed
US-20130022570-A1 CROSSLINKED POLYVINYLAMINE, POLYALLYLAMINE, AND POLYETHYLENEIMINE FOR USE AS BILE ACID SEQUESTRANTS RELYPSA, INC. (US) 2013-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839657-B2 Ionizable lipids and compositions for nucleic acid delivery POLRMT, POLN, NPC1L1 ZDHHC20 1521/4885ZDHHC2 1295/4885EPHX2 3604/4885
US-20130022570-A1 CROSSLINKED POLYVINYLAMINE, POLYALLYLAMINE, AND POLYETHYLENEIMINE FOR USE AS BILE ACID SEQUESTRANTS NR1H4, SLC10A2, GPBAR1 ZDHHC20 3420/4885ZDHHC2 3668/4885EPHX2 2002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.