SCHEMBL2368015

SCHEMBL2368015

C=C(CC(=O)O)C(=O)OCC(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367325 0.93 THRB (0.37) ALOX15HSD17B10THRB
SCHEMBL1681694 0.89 ALOX15 (0.34) ALOX15HSD17B10TET2
SCHEMBL2367786 0.84 TSHR (0.35)
SCHEMBL906211 0.82 HTT (0.42) ALOX15HSD17B10
SCHEMBL16174485 0.82 USP2 (0.41)
SCHEMBL29038819 0.81
SCHEMBL3610810 0.80
SCHEMBL5889660 0.80 HTT (0.30)
SCHEMBL2368189 0.78 THRB (0.35) THRB
SCHEMBL15153754 0.78 THRB (0.35) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed