SCHEMBL906211

SCHEMBL906211

C=C(CC(=O)O)C(=O)OCC(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FABP7 O15540 1/20 0.32
LDHA P00338 1/20 0.31
SRR Q9GZT4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681694 0.85 ALOX15 (0.34) ALOX15HSD17B10
SCHEMBL941246 0.84 HTT (0.42) HTT
SCHEMBL2368015 0.82 ALOX15 (0.32) ALOX15HSD17B10
SCHEMBL2367717 0.82 LMNA (0.39) ALOX15HSD17B10
SCHEMBL24387394 0.80 ALOX15 (0.36) ALOX15HSD17B10LDHASRR
SCHEMBL6597149 0.80 ALOX15 (0.36) ALOX15HSD17B10LDHASRR
SCHEMBL9546008 0.79 HTT (0.45) HTTFABP7
SCHEMBL23979702 0.79 HTT (0.45) HTTFABP7
SCHEMBL10204704 0.79 HTT (0.45) HTTFABP7
SCHEMBL2367325 0.79 THRB (0.37) ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194479-B1 PROCESS FOR MAKING FLUORINATED POLYMER ADSORBENT PARTICLES PROMETIC BIOSCIENCES INC (CA) 2004-02-18 EP claimed
US-5346978-A Polymeric compositions useful in oxygen permeable contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1994-09-13 US claimed
EP-0242080-B1 COPOLYMER COMPOSITIONS PARAGON OPTICAL INC (US) 1992-12-16 EP claimed
US-9182674-B2 Immersion upper layer film forming composition and method of forming photoresist pattern JSR CORPORATION (JP) 2015-11-10 US disclosed
EP-2468780-B1 Copolymer and top coating composition JSR CORP (JP) 2013-11-13 EP disclosed
US-8580482-B2 Copolymer and top coating composition JSR CORPORATION (JP) 2013-11-12 US disclosed
CN-101080674-B Composition for forming antireflection film, layered product, and method for forming resist pattern JSR CORP 2013-09-18 CN disclosed
EP-1806370-B1 COPOLYMER AND UPPER FILM-FORMING COMPOSITION JSR CORP (JP) 2013-05-22 EP disclosed
EP-2277929-B1 Copolymer and top coating composition JSR CORP (JP) 2012-11-21 EP disclosed
US-20120282553-A1 IMMERSION UPPER LAYER FILM FORMING COMPOSITION AND METHOD OF FORMING PHOTORESIST PATTERN JSR CORPORATION (JP) 2012-11-08 US disclosed
EP-2315078-B1 Upper layer film forming composition for liquid immersion and method of forming photoresist pattern JSR CORP (JP) 2012-10-17 EP disclosed
US-5128434-A Contact lenses BAUSCH & LOMB INCORPORATED (US) 1992-07-07 US disclosed
CN-1061980-A The control of hard segment size in the urethane forming process BAUSCH & LOMB (US) 1992-06-17 CN disclosed
EP-0481431-A2 Pressurized fluid composition and process for making same UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION, Three Cristina Centre (US) 1992-04-22 EP disclosed
US-5034461-A Polyetherurethanesiloxane copolymer for contact lenses, also containing acrylate groups to provide high oxygen permeability BAUSCH & LOMB INCORPORATED (US) 1991-07-23 US disclosed
US-4996275-A With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance POLYMER TECHNOLOGY CORPORATION (US) 1991-02-26 US disclosed
EP-0401990-A2 Prepolymers useful in biomedical devices BAUSCH & LOMB INCORPORATED (US) 1990-12-12 EP disclosed
US-4686267-A Fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-08-11 US disclosed
EP-0219312-A2 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-04-22 EP disclosed
US-4602074-A SILICON CONTAINING ACRYLIC MONOMER NIPPON CONTACT LENS MANUFACTURING LTD. (JP) 1986-07-22 US disclosed