SCHEMBL2368028

SCHEMBL2368028

C=C(C(=O)OC)C(CCC[SiH](O[Si](C)(C)C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18628093 0.87
SCHEMBL6657457 0.75 CA2 (0.43)
SCHEMBL9743530 0.73 ALDH1A1 (0.31)
SCHEMBL5282994 0.72 CHRM1 (0.43) TGFBR1
SCHEMBL9172414 0.71 TGFBR1 (0.40) TGFBR1
SCHEMBL2368241 0.69
SCHEMBL5276347 0.67 ALDH1A1 (0.41) TGFBR1
SCHEMBL2379047 0.67
SCHEMBL12095005 0.67 TSHR (0.32)
Methacrylic Acid SCHEMBL11546414 0.66 ALDH1A1 (0.42) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed