Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297341 | 0.78 | NPC1 (0.55) | MEN1KMT2ARAB9ASMN1; SMN2POLB | |
| SCHEMBL16994790 | 0.76 | TSHR (0.63) | MEN1KMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL27420904 | 0.74 | ALK (0.45) | RAB9AHPGDNPC1CCR5TP53 | |
| SCHEMBL27417456 | 0.74 | ALK (0.45) | RAB9AHPGDNPC1CCR5TP53 | |
| SCHEMBL11750662 | 0.74 | RAB9A (0.48) | MEN1KMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL10195738 | 0.74 | ALDH1A1 (0.66) | MEN1KMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL15975482 | 0.74 | HPGD (1.00) | MEN1KMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL965553 | 0.73 | ATM (0.50) | KMT2ARAB9AHPGDPOLBNPC1 | |
| SCHEMBL4979867 | 0.72 | CCR5 (0.71) | KMT2APOLBCCR5CYP3A4CYP2C19 | |
| SCHEMBL8130980 | 0.72 | POLB (0.62) | MEN1KMT2ARAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854394-A1 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |