Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 10/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501802 | 1.00 | HCRTR1 (0.34) | HCRTR1CDK9CCNT1ANO1IDO1 | |
| SCHEMBL23680931 | 0.88 | NR3C2 (0.34) | HCRTR1CDK9CCNT1ANO1KIT | |
| SCHEMBL29501811 | 0.88 | NR3C2 (0.34) | HCRTR1CDK9CCNT1ANO1KIT | |
| SCHEMBL29501787 | 0.84 | LMNA (0.34) | ANO1KDR | |
| SCHEMBL23680937 | 0.84 | LMNA (0.34) | ANO1KDR | |
| SCHEMBL23680918 | 0.80 | IDO1 (0.35) | IDO1 | |
| SCHEMBL29501757 | 0.80 | IDO1 (0.35) | IDO1 | |
| SCHEMBL23680940 | 0.76 | MET (0.33) | HCRTR1CDK9CCNT1KITAXL | |
| SCHEMBL23680929 | 0.76 | MET (0.33) | HCRTR1IDO1KITAXLKDR | |
| SCHEMBL29501723 | 0.76 | MET (0.33) | HCRTR1IDO1KITAXLKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210227826-A1 | Microbiocidal Picolinamide Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210227826-A1 | Microbiocidal Picolinamide Derivatives | CASP2, CASP1, MSR1 | HCRTR1 118/4885CDK9 4743/4885CCNT1 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.