Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367611 | 0.93 | MAOA (0.36) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2368067 | 0.92 | MAOA (0.35) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2367649 | 0.87 | MAOA (0.36) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2367479 | 0.83 | — | — | |
| SCHEMBL886910 | 0.82 | MAOA (0.40) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL8383505 | 0.80 | MAOA (0.44) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7990104 | 0.77 | MAOA (0.56) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL184898 | 0.77 | MAOA (0.46) | MAOAMAOBSLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2367916 | 0.73 | MAOA (0.33) | MAOAMAOBSLC6A4SLC6A3 | |
| SCHEMBL22373762 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |