Sugi Predict

Sugi Predict / Compounds / SCHEMBL2367916

SCHEMBL2367916

SCHEMBL2367916

C=C(CC[SiH](O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 6/20 0.33
▸ MAOB P27338 6/20 0.33
▸ SLC6A4 P31645 1/20 0.32
▸ SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368067 0.76 MAOA (0.35) MAOAMAOBSLC6A4SLC6A3
SCHEMBL2368282 0.73 MAOA (0.38) MAOAMAOBSLC6A4SLC6A3
SCHEMBL2367611 0.71 MAOA (0.36) MAOAMAOBSLC6A4SLC6A3
SCHEMBL2367927 0.68 IDO1 (0.40) —
SCHEMBL7990104 0.67 MAOA (0.56) MAOAMAOBSLC6A4SLC6A3
SCHEMBL8383505 0.67 MAOA (0.44) MAOAMAOBSLC6A4SLC6A3
SCHEMBL15841416 0.66 MAOA (0.40) MAOAMAOBSLC6A4SLC6A3
SCHEMBL2367649 0.65 MAOA (0.36) MAOAMAOBSLC6A4SLC6A3
SCHEMBL184898 0.64 MAOA (0.46) MAOAMAOBSLC6A4SLC6A3
SCHEMBL78217 0.64 CES2 (0.52) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 — — US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 — — US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 — — EP disclosed