Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383505 | 0.84 | MAOA (0.44) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL2368282 | 0.77 | MAOA (0.38) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL7990104 | 0.76 | MAOA (0.56) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL3747872 | 0.76 | MAOA (0.48) | MAOAMAOBMAPTALDH1A1MAPK1 | |
| SCHEMBL886910 | 0.76 | MAOA (0.40) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL2367611 | 0.74 | MAOA (0.36) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL2367649 | 0.74 | MAOA (0.36) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL2368067 | 0.73 | MAOA (0.35) | MAOAMAOBSLC6A4SLC6A3MAPT | |
| SCHEMBL78217 | 0.73 | CES2 (0.52) | MAOAMAOBLMNA | |
| SCHEMBL810101 | 0.73 | MAOA (0.48) | MAOAMAOBSLC6A4SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054095-B1 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | BOSTON SCIENT LTD (BM) | 2016-08-24 | — | — | EP | disclosed |
| US-8367096-B2 | Polymers having covalently bound therapeutic agents | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8092821-B2 | Medical devices having polymeric regions with improved adhesion | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2400998-A2 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | Boston Scientific Scimed, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| EP-2054100-B1 | MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH IMPROVED ADHESION | BOSTON SCIENT LTD (BB) | 2011-03-23 | — | — | EP | disclosed |
| US-7897170-B2 | Medical devices having improved mechanical performance | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897171-B2 | Medical devices having improved mechanical performance | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| WO-2010099260-A2 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-09-02 | — | — | WO | disclosed |
| US-20090186067-A1 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| EP-2054100-A2 | MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH IMPROVED ADHESION | Boston Scientific Scimed, Inc. (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008027107-A2 | MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH IMPROVED ADHESION | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| US-20080051541-A1 | Medical devices having improved mechanical performance | BOSTON SCIENTIFIC SCIMED, INC. | 2008-02-28 | — | — | US | disclosed |
| US-20080051542-A1 | Medical devices having polymeric regions with improved adhesion | STRICKLER FREDERICK H | 2008-02-28 | — | — | US | disclosed |
| WO-2008024510-A2 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| US-20070020308-A1 | Polymers having covalently bound therapeutic agents | BOSTON SCIENTIFIC SCIMED, INC. | 2007-01-25 | — | — | US | disclosed |
| WO-2007012013-A2 | POLYMER CONJUGATES TO THERAPEUTIC AGENTS VIA AN SI-N AND/OR AN SI-O LINKAGE | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| US-6469115-B1 | ROOM TEMPERATURE VULCANIZABLE POLYISOBUTYLENE POLYMER HAVING HYDROLYZABLE SILYL- FUNCTIONAL GROUPS POSITIONED AT OR NEAR MOLECULAR CHAIN ENDS | DOW CORNING CORPORATION | 2002-10-22 | — | — | US | disclosed |
| WO-2002028924-A1 | SILYL-FUNCTIONAL PSEUDO-TELECHELIC POLYISOBUTYLENE TERPOLYMERS | DOW CORNING CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2001087999-A2 | VIRTUALLY TELECHELIC SILYL-FUNCTIONAL POLYISOBUTYLENE | DOW CORNING CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| US-6268451-B1 | POLYMERS OF ISOBUTYLENE, ISOPRENYLPHENYL AND VINYLPHENYL WITH SILYLALKYL GROUPS WITH SOLVENTS | UNIVERSITY OF MASSACHUSETTS LOWELL | 2001-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186067-A1 | MEDICAL DEVICES HAVING IMPROVED MECHANICAL PERFORMANCE | PIGS, TNNI3, TNNC1 | MAOA 3632/4885MAOB 2371/4885SLC6A4 3631/4885 |
| US-20070020308-A1 | Polymers having covalently bound therapeutic agents | CD44, CD47, PAICS | MAOA 2239/4885MAOB 2639/4885SLC6A4 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.