Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PPM1D | O15297 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CCL2 | P13500 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260217 | 1.00 | SLC7A5 (0.51) | SLC7A5MRGPRX4CASRLOXL2PPM1D | |
| SCHEMBL16355841 | 0.82 | SLC7A5 (0.48) | SLC7A5MRGPRX4CASRLOXL2CYP4F2 | |
| SCHEMBL23684547 | 0.80 | GRIK1 (0.51) | MRGPRX4PPM1DOPRM1OPRD1OPRK1 | |
| SCHEMBL12301533 | 0.76 | SLC7A5 (0.65) | SLC7A5MRGPRX4LOXL2CYP4F2CYP4A11 | |
| SCHEMBL757429 | 0.76 | LOXL2 (0.62) | SLC7A5MRGPRX4LOXL2PPM1DCYP4F2 | |
| SCHEMBL17982809 | 0.75 | KDM4E (0.56) | LOXL2LMNATP53 | |
| SCHEMBL3499880 | 0.75 | SLC7A5 (0.63) | SLC7A5MRGPRX4LOXL2CYP4F2CYP4A11 | |
| SCHEMBL7384982 | 0.75 | SLC7A5 (0.63) | SLC7A5MRGPRX4LOXL2CYP4F2CYP4A11 | |
| SCHEMBL5732970 | 0.75 | LMNA (0.38) | MRGPRX4BRD4CCL2OPRM1OPRD1 | |
| SCHEMBL4928282 | 0.74 | LOXL2 (0.69) | SLC7A5MRGPRX4LOXL2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | XDH, F12, LPXN | SLC7A5 2181/4885MRGPRX4 62/4885CASR 2994/4885 |
| US-11077101-B1 | Compounds and methods of use | XDH, F12, LPXN | SLC7A5 2181/4885MRGPRX4 62/4885CASR 2994/4885 |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | XDH, F12, LPXN | SLC7A5 2181/4885MRGPRX4 62/4885CASR 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.