SCHEMBL2368449

SCHEMBL2368449

Oc1c(Br)cc2c(Br)c(O)c(Br)cc2c1Br

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA4 P22748 3/20 0.52
CA6 P23280 3/20 0.52
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
AKR1B1 P15121 3/20 0.44
PTPN1 P18031 1/20 0.44
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
ALOX15 P16050 3/20 0.40
TTR P02766 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
RECQL P46063 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11272164 0.88 CA1 (0.52) CA1CA2CA4CA6CYP3A4
SCHEMBL30310848 0.88 CA1 (0.52) CA1CA2CA4CA6CYP3A4
SCHEMBL69904 0.80 CA1 (0.67) CA1CA2CA4CA6CYP3A4
SCHEMBL28017537 0.78 CA1 (0.63) CA1CA2CA4CA6CYP3A4
SCHEMBL9472226 0.75 CA1 (0.68) CA1CA2CA4CA6CYP3A4
SCHEMBL2368058 0.75 CA1 (0.41) CA1CA2CA4CA6CYP3A4
SCHEMBL6600451 0.73 POLB (0.52) CA1CA2CA4CA6TDP1
SCHEMBL7039369 0.73 GABRA1 (0.55) CA1CA2CA4CA6CYP3A4
SCHEMBL11882654 0.73 PTPN1 (0.60) CA1CA2CA4CA6CYP3A4
SCHEMBL68947 0.73 PTPN1 (0.54) CA1CA2CA4CA6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961326-A Naphtho-difurane conjugated polymer and preparation method and application thereof 北京航空航天大学 2021-06-15 CN claimed
CN-112961326-A Naphtho-difurane conjugated polymer and preparation method and application thereof 北京航空航天大学 2021-06-15 CN disclosed
US-10622572-B2 Organic thin-film transistor and method for manufacturing the same, material for organic thin-film transistor, composition for organic thin-film transistor, compound, and organic semiconductor film FUJIFILM CORPORATION (JP) 2020-04-14 US disclosed
US-20180159053-A1 ORGANIC THIN-FILM TRANSISTOR AND METHOD FOR MANUFACTURING THE SAME, MATERIAL FOR ORGANIC THIN-FILM TRANSISTOR, COMPOSITION FOR ORGANIC THIN-FILM TRANSISTOR, COMPOUND, AND ORGANIC SEMICONDUCTOR FILM FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
US-20180159053-A1 ORGANIC THIN-FILM TRANSISTOR AND METHOD FOR MANUFACTURING THE SAME, MATERIAL FOR ORGANIC THIN-FILM TRANSISTOR, COMPOSITION FOR ORGANIC THIN-FILM TRANSISTOR, COMPOUND, AND ORGANIC SEMICONDUCTOR FILM FUJIFILM CORPORATION (JP) 2018-06-07 US disclosed
EP-2368892-B1 NOVEL COMPOUND, PROCESS FOR PRODUCING THE COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE UNIV HIROSHIMA (JP) 2014-12-03 EP disclosed
EP-2368892-B1 NOVEL COMPOUND, PROCESS FOR PRODUCING THE COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE UNIV HIROSHIMA (JP) 2014-12-03 EP disclosed
US-8816100-B2 Compound, method of producing the compound, organic semiconductor material and organic semiconductor device HIROSHIMA UNIVERSITY (JP) 2014-08-26 US disclosed
US-8816100-B2 Compound, method of producing the compound, organic semiconductor material and organic semiconductor device HIROSHIMA UNIVERSITY (JP) 2014-08-26 US disclosed
US-8816100-B2 Compound, method of producing the compound, organic semiconductor material and organic semiconductor device HIROSHIMA UNIVERSITY (JP) 2014-08-26 US disclosed
EP-2368892-A1 NOVEL COMPOUND, PROCESS FOR PRODUCING THE COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE Hiroshima University (JP) 2011-09-28 EP disclosed
EP-2368892-A1 NOVEL COMPOUND, PROCESS FOR PRODUCING THE COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE Hiroshima University (JP) 2011-09-28 EP disclosed
US-20110224445-A1 Novel Compound, Method of Producing the Compound, Organic Semiconductor Material and Organic Semiconductor Device HIROSHIMA UNIVERSITY (JP) 2011-09-15 US disclosed
US-20110224445-A1 Novel Compound, Method of Producing the Compound, Organic Semiconductor Material and Organic Semiconductor Device HIROSHIMA UNIVERSITY (JP) 2011-09-15 US disclosed
US-20110224445-A1 Novel Compound, Method of Producing the Compound, Organic Semiconductor Material and Organic Semiconductor Device HIROSHIMA UNIVERSITY (JP) 2011-09-15 US disclosed
WO-2010058692-A1 NOVEL COMPOUND, PROCESS FOR PRODUCING THE COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC SEMICONDUCTOR DEVICE 国立大学法人広島大学 (JP) 2010-05-27 WO disclosed
EP-0664014-B1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL NV (NL) 1998-08-19 EP disclosed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed
EP-0664014-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS Akzo Nobel N.V. (NL) 1995-07-26 EP disclosed
WO-1994008269-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180159053-A1 ORGANIC THIN-FILM TRANSISTOR AND METHOD FOR MANUFACTURING THE SAME, MATERIAL FOR ORGANIC THIN-FILM TRANSISTOR, COMPOSITION FOR ORGANIC THIN-FILM TRANSISTOR, COMPOUND, AND ORGANIC SEMICONDUCTOR FILM SLCO2A1, SLCO4C1, SLCO2B1 CA1 1854/4885CA2 3830/4885CA4 2271/4885
US-10622572-B2 Organic thin-film transistor and method for manufacturing the same, material for organic thin-film transistor, composition for organic thin-film transistor, compound, and organic semiconductor film SLCO2A1, SLCO4C1, SLCO2B1 CA1 1854/4885CA2 3830/4885CA4 2271/4885
US-20110224445-A1 Novel Compound, Method of Producing the Compound, Organic Semiconductor Material and Organic Semiconductor Device TST, SCLY, SELENOI CA1 1041/4885CA2 3159/4885CA4 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.