Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | WHR1 | P49842 | 3/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685049 | 0.89 | HRH3 (0.41) | FPR2SCN9AWHR1CCR4PRMT5 | |
| SCHEMBL23684020 | 0.88 | MET (0.40) | FPR2SCN9APRMT5WDR77KDM4E | |
| SCHEMBL23684719 | 0.87 | KDM4E (0.42) | PRMT5WDR77KDM4EMEN1ALDH1A1 | |
| SCHEMBL23684624 | 0.86 | PIK3CA (0.43) | ACHEPTPN11KDM4EMEN1ALDH1A1 | |
| SCHEMBL23304360 | 0.85 | GAA (0.40) | KDM4EMEN1ALDH1A1GAATHRB | |
| SCHEMBL23304407 | 0.85 | ALDH1A1 (0.46) | KDM4EMEN1ALDH1A1GAATHRB | |
| SCHEMBL23684344 | 0.84 | RAD52 (0.42) | PRMT5WDR77PTPN11EHMT2EHMT1 | |
| SCHEMBL23684778 | 0.84 | RBP4 (0.38) | FPR2SCN9APRMT5WDR77KDM4E | |
| SCHEMBL23684010 | 0.83 | GBA1 (0.39) | KDM4EMEN1ALDH1A1GAATHRB | |
| SCHEMBL17303784 | 0.82 | ALDH1A1 (0.48) | ACHECCR4EHMT2EHMT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | XDH, F12, LPXN | FPR2 298/4885SCN9A 1065/4885ACHE 375/4885 |
| US-11077101-B1 | Compounds and methods of use | XDH, F12, LPXN | FPR2 298/4885SCN9A 1065/4885ACHE 375/4885 |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | XDH, F12, LPXN | FPR2 298/4885SCN9A 1065/4885ACHE 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.