Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580096 | 0.85 | SCN3A (0.54) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL21580127 | 0.81 | SCN3A (0.52) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL21580116 | 0.81 | SCN3A (0.51) | HPGDSCN3ASCN9ASMN1; SMN2MAOB | |
| SCHEMBL21580134 | 0.80 | SCN3A (0.55) | ALDH1A1SCN3ASCN9ASMN1; SMN2MAOB | |
| SCHEMBL21580107 | 0.79 | SCN3A (0.52) | ALDH1A1HPGDSCN3ASCN9ASMN1; SMN2 | |
| SCHEMBL21580137 | 0.79 | SCN3A (0.54) | ALDH1A1SCN3ASCN9ASMN1; SMN2NPC1 | |
| SCHEMBL12838360 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL21580166 | 0.78 | L3MBTL1 (0.51) | ALDH1A1HPGDL3MBTL1SCN3ASCN9A | |
| SCHEMBL21580126 | 0.78 | SCN3A (0.56) | ALDH1A1POLBSCN3ASCN9ASMN1; SMN2 | |
| SCHEMBL21580123 | 0.77 | TSHR (0.57) | HPGDSCN3ASCN9ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230157-A1 | PAIN TREATING COMPOUNDS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230157-A1 | PAIN TREATING COMPOUNDS AND USES THEREOF | TRPV1, TRPA1, TRPV3 | ALDH1A1 768/4885CYP1A2 2613/4885POLB 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.