Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 10/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123772 | 1.00 | PRMT5 (0.42) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL19667421 | 0.83 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL7114998 | 0.83 | PRMT5 (0.38) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL23892218 | 0.78 | PRMT5 (0.47) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL16769947 | 0.78 | PRMT5 (0.44) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL23535896 | 0.78 | NNMT (0.38) | SLC22A12NNMT | |
| SCHEMBL4352091 | 0.76 | ADCY5 (0.45) | — | |
| SCHEMBL30897109 | 0.76 | ADCY5 (0.45) | — | |
| SCHEMBL8885246 | 0.76 | ADCY5 (0.45) | — | |
| SCHEMBL18571707 | 0.75 | ABL1 (0.44) | PRMT5WDR77SLC22A12NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | PRMT5 3886/4885WDR77 2625/4885SLC22A12 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.