Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 10/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23692929 | 1.00 | PRMT5 (0.42) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL19667421 | 0.83 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL7114998 | 0.83 | PRMT5 (0.38) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL23892218 | 0.78 | PRMT5 (0.47) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL16769947 | 0.78 | PRMT5 (0.44) | PRMT5WDR77SLC22A12NNMT | |
| SCHEMBL23535896 | 0.78 | NNMT (0.38) | SLC22A12NNMT | |
| SCHEMBL4352091 | 0.76 | ADCY5 (0.45) | — | |
| SCHEMBL30897109 | 0.76 | ADCY5 (0.45) | — | |
| SCHEMBL8885246 | 0.76 | ADCY5 (0.45) | — | |
| SCHEMBL18571707 | 0.75 | ABL1 (0.44) | PRMT5WDR77SLC22A12NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |