Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 12/20 | 0.46 |
| ▸ | CTSS | P25774 | 13/20 | 0.45 |
| ▸ | CTSB | P07858 | 12/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693699 | 0.83 | CTSS (0.42) | CTSLCTSSCTSBCTSKF10 | |
| SCHEMBL23673493 | 0.82 | CTSB (0.57) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL23693289 | 0.79 | CTSL (0.52) | CTSLCTSSCTSBCTSKF10 | |
| SCHEMBL23693711 | 0.79 | CTSL (0.56) | CTSLCTSSCTSBCTSK | |
| SCHEMBL23693973 | 0.78 | F10 (0.42) | CTSLCTSSCTSBCTSKF10 | |
| SCHEMBL23693620 | 0.78 | CTSB (0.54) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL6184450 | 0.77 | CTSL (0.72) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL23673484 | 0.76 | CTSL (0.50) | CTSLCTSSCTSBCTSKF10 | |
| Trifluoroacetic Acid SCHEMBL23673580 | 0.74 | CTSB (0.49) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL23693873 | 0.74 | CTSB (0.47) | CTSLCTSSCTSBCTSKCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |