SCHEMBL2369351

SCHEMBL2369351

C=C(C)C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=O)C(=O)O)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ C3AR1 Q16581 1/20 0.39
▸ FURIN P09958 7/20 0.36
▸ CTDSP1 Q9GZU7 1/20 0.35
▸ CTSB P07858 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ PRSS1 P07477 1/20 0.34
▸ NOD1 Q9Y239 2/20 0.34
▸ TGFBR1 P36897 1/20 0.33
▸ SHMT1 P34896 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KLK7 P49862 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ FOLH1 Q04609 1/20 0.33
▸ GNPAT O15228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31319761 0.87 C3AR1 (0.41) C3AR1FURINCTDSP1CTSBPRSS1
SCHEMBL29620243 0.87 C3AR1 (0.42) C3AR1FURINCTDSP1PRSS1NOD1
SCHEMBL24191073 0.86 C3AR1 (0.42) C3AR1FURINCTDSP1CTSBPOLB
SCHEMBL30317564 0.86 C3AR1 (0.42) C3AR1FURINCTDSP1CTSBPOLB
SCHEMBL23629902 0.82 MEN1 (0.44) C3AR1FURINPRSS1MEN1KMT2A
SCHEMBL29385639 0.81 C3AR1 (0.45) C3AR1FURINCTDSP1POLBNOD1
SCHEMBL31666024 0.81 NOD1 (0.40) C3AR1FURINCTDSP1PRSS1NOD1
SCHEMBL18688864 0.81 GNPAT (0.45) C3AR1FURINCTDSP1NOD1FOLH1
SCHEMBL28574926 0.81 GNPAT (0.45) C3AR1FURINCTDSP1NOD1FOLH1
Trifluoroacetic Acid SCHEMBL23630136 0.80 QRFPR (0.39) C3AR1FURINCTDSP1CTSBPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2544701-B1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF UNIV UTAH RES FOUND (US) 2019-08-14 — — EP disclosed
US-9289510-B2 Polymeric drug delivery conjugates and methods of making and using thereof UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2016-03-22 — — US disclosed
US-20130156722-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-06-20 — — US disclosed
EP-2544701-A2 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF University of Utah Research Foundation (US) 2013-01-16 — — EP disclosed
WO-2011112482-A2 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2011-09-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130156722-A1 POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF CD44, MMP7, MMP26 C3AR1 1563/4885FURIN 76/4885CTDSP1 605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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