⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747302 | 0.81 | MDM2 (0.31) | — | |
| SCHEMBL18406777 | 0.76 | SIGMAR1 (0.32) | — | |
| SCHEMBL23697467 | 0.75 | ALOX15 (0.35) | — | |
| SCHEMBL10955587 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL5949792 | 0.72 | OPRM1 (0.30) | — | |
| SCHEMBL10140538 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL8406286 | 0.72 | SIGMAR1 (0.34) | — | |
| SCHEMBL19012529 | 0.72 | — | — | |
| SCHEMBL19001055 | 0.70 | ATM (0.33) | — | |
| SCHEMBL24424171 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026041607-A1 | AZIRIDINYL-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO (NETHERLANDS) B.V. (NL) | 2026-02-26 | — | — | WO | disclosed |
| US-12247008-B2 | Multi-aziridine compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-03-11 | — | — | US | disclosed |
| US-20230136495-A1 | MULTI-AZIRIDINE COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-05-04 | — | — | US | disclosed |
| US-20230136495-A1 | MULTI-AZIRIDINE COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-05-04 | — | — | US | disclosed |
| US-20230136495-A1 | MULTI-AZIRIDINE COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-05-04 | — | — | US | disclosed |
| EP-4093794-A1 | MULTI-AZIRIDINE COMPOUND | Covestro (Netherlands) B.V. (NL) | 2022-11-30 | — | — | EP | disclosed |
| CN-114945614-A | Polyaziridine compounds | 科思创(荷兰)有限公司 | 2022-08-26 | — | — | CN | disclosed |
| WO-2021148568-A1 | MULTI-AZIRIDINE COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021148568-A1 | MULTI-AZIRIDINE COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |