SCHEMBL23699018

SCHEMBL23699018

OC1(O)Cc2ccccc2OC1c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.37
ADORA3 P0DMS8 2/20 0.37
AR P10275 2/20 0.37
CYP19A1 P11511 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NISCH Q9Y2I1 1/20 0.36
PTGS2 P35354 1/20 0.36
DNMT3B Q9UBC3 1/20 0.35
HSP90AB1 P08238 1/20 0.34
NPC1 O15118 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
TRPA1 O75762 1/20 0.33
MAOA P21397 6/20 0.32
AOC2 O75106 5/20 0.32
PSMB5 P28074 1/20 0.32
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6256448 0.75 CA2 (0.38) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL28030160 0.67 NISCH (0.37) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL29935960 0.65 MAOB (0.42) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL5722720 0.65 MAOB (0.42) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL403523 0.64 MAOB (0.65) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL32498549 0.64 MAOB (0.65) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL5313705 0.64 DNMT3B (0.57) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL1659934 0.64 CYP3A4 (0.48) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL460037 0.64 CYP3A4 (0.48) MAOBADORA3ARCYP19A1KDM4E
SCHEMBL460038 0.64 CYP3A4 (0.48) MAOBADORA3ARCYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4096436-B1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION ANALYTICON DISCOVERY GMBH (DE) 2024-04-17 EP disclosed
US-20230248034-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION ANALYTICON DISCOVERY GMBH (DE) 2023-08-10 US disclosed
WO-2023131545-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN Biotech AG (DE) 2023-07-13 WO disclosed
US-20230142789-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION ANALYTICON DISCOVERY GMBH (DE) 2023-05-11 US disclosed
EP-4096435-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN AG (DE) 2022-12-07 EP disclosed
EP-4096436-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN AG (DE) 2022-12-07 EP disclosed
EP-4096437-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN AG (DE) 2022-12-07 EP disclosed
WO-2021152028-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN AG (DE) 2021-08-05 WO disclosed
WO-2021152064-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN AG (DE) 2021-08-05 WO disclosed
WO-2021151988-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION BRAIN AG (DE) 2021-08-05 WO disclosed
EP-3858155-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION Analyticon Discovery GmbH (DE) 2021-08-04 EP disclosed
CN-103442709-A Pharmaceutical composition for treating liver diseases IND TECH RES INST 2013-12-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248034-A1 A SWEETENER OR SWEETNESS ENHANCER COMPOSITION TAS2R40, TAS2R30, TAS2R60 MAOB 4218/4885ADORA3 388/4885AR 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.