Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31548185 | 0.88 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL31548247 | 0.86 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGCYP2C19 | |
| SCHEMBL2800319 | 0.84 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL23699085 | 0.83 | CYP11B2 (0.46) | PIK3CDCYP11B2GPR119EHMT2PARP1 | |
| SCHEMBL23707519 | 0.83 | CYP11B2 (0.44) | CYP11B2GPR119EHMT2PARP1 | |
| SCHEMBL31548111 | 0.78 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL29331856 | 0.77 | ABHD6 (0.54) | CYP11B2GPR119 | |
| SCHEMBL12277300 | 0.77 | GPR119 (0.67) | GPR119 | |
| SCHEMBL31548191 | 0.77 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL31548249 | 0.76 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12551478-B2 | Quinoline derivative having indoleamine-2,3-dioxygenase inhibitory activity | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2026-02-17 | — | — | US | disclosed |
| US-20210379052-A1 | QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2021-12-09 | — | — | US | disclosed |
| EP-3858813-A1 | QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858813-A1 | QUINOLONE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITED ACTIVITY | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12551478-B2 | Quinoline derivative having indoleamine-2,3-dioxygenase inhibitory activity | IDO2, IDO1, HDAC2 | PIK3CD 2260/4885PIK3CA 3498/4885PIK3CB 2741/4885 |
| US-20210379052-A1 | QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY | IDO1, IDO2, INMT | PIK3CD 2892/4885PIK3CA 3794/4885PIK3CB 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.