Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699239 | 0.90 | DRD2 (0.45) | DRD2SYKMTNR1AMTNR1BPCSK9 | |
| SCHEMBL23699407 | 0.83 | DRD2 (0.44) | DRD2SYKACE | |
| SCHEMBL23699443 | 0.78 | USP2 (0.43) | MTNR1AMTNR1BUSP2TSHR | |
| SCHEMBL23934503 | 0.77 | USP2 (0.45) | MTNR1AMTNR1BUSP2TSHR | |
| SCHEMBL23934534 | 0.77 | DRD2 (0.38) | DRD2MTNR1AMTNR1BUSP2TSHR | |
| SCHEMBL31758027 | 0.76 | DRD2 (0.41) | DRD2SCN9A | |
| SCHEMBL31757665 | 0.76 | DRD2 (0.41) | DRD2SCN9A | |
| SCHEMBL24106073 | 0.75 | USP2 (0.54) | USP2TSHREPHX2SCN9A | |
| SCHEMBL23771659 | 0.74 | PPARA (0.40) | DRD2 | |
| SCHEMBL22036215 | 0.74 | PPARA (0.40) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |