Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | ECE1 | P42892 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699239 | 0.93 | DRD2 (0.45) | DRD2ECE1SYKACE | |
| SCHEMBL23699401 | 0.83 | DRD2 (0.44) | DRD2SYKACE | |
| SCHEMBL29535205 | 0.81 | ALDH1A1 (0.43) | DRD2ECE1ALDH1A1MAPK1MAPK14 | |
| SCHEMBL26619620 | 0.81 | ALDH1A1 (0.43) | DRD2ECE1ALDH1A1MAPK1MAPK14 | |
| SCHEMBL26619622 | 0.81 | ALDH1A1 (0.43) | DRD2ECE1ALDH1A1MAPK1MAPK14 | |
| SCHEMBL23771659 | 0.76 | PPARA (0.40) | DRD2ECE1 | |
| SCHEMBL7958217 | 0.76 | PPARA (0.40) | DRD2ECE1 | |
| SCHEMBL22035427 | 0.76 | PPARA (0.40) | DRD2ECE1 | |
| SCHEMBL22036215 | 0.76 | PPARA (0.40) | DRD2ECE1 | |
| SCHEMBL1915907 | 0.76 | PPARA (0.40) | DRD2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |