Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699389 | 1.00 | CNR2 (0.44) | CNR2OPRM1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL23699049 | 0.88 | LMNA (0.50) | CYP2C9CYP2C19CTSSCTSLLMNA | |
| SCHEMBL23699046 | 0.88 | LMNA (0.50) | CYP2C9CYP2C19CTSSCTSLLMNA | |
| SCHEMBL23699390 | 0.87 | SYK (0.44) | CNR2OPRM1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL23699393 | 0.87 | SYK (0.44) | CNR2OPRM1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL17825663 | 0.84 | CNR2 (0.47) | CNR2OPRM1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL23699376 | 0.82 | CTSS (0.45) | CNR2OPRM1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL23699379 | 0.82 | CTSS (0.45) | CNR2OPRM1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL23699398 | 0.81 | LMNA (0.45) | CTSSCTSLLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23699400 | 0.81 | LMNA (0.45) | CTSSCTSLLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |